The Substance is all about showing instead of telling, and while that ultimately proves to be exceptionally demanding for the film’s stars, both Demi Moore and Margaret Qualley are magnificent. Beyond the intense physicality for both actors – including bold nudity and metamorphosis – they are what set the stakes and attitude.

What is The Substance? It's a drug that will create a younger version of you from your own DNA. That new you will graphically fall out of your back, complete with squishy sound effects.

The Substance” is more than just blood and guts — it’s got a career-topping performance by Demi Moore, who is worthy of serious Oscar consideration. In Coralie Fargeat’s daring body horror film Moore delivers possibly her most daring role ever.

The actress stars alongside Margaret Qualley and Dennis Quaid in Coralie Fargeat’s gleefully grotesque movie about an aging celebrity who takes an experimental drug that gives her a younger self.

With "The Substance," writer-director Coralie Fargeat summarily burns that door to the ground and kicks the ashes around with a gleeful laugh. The independent horror movie builds on themes from classic literature to TikTok influencers to take an unflinching and desperate look at the damage that hating one's body can do,

It's not long before Demi and her doppelganger are at each other's throats. Complications ensue when Sue is hired by Elisabeth's old boss (Quaid is scarily hilarious as Harvey) to star in a new workout show called "Pump It Up.

Coralie Fargeat’s sci-fi shocker follows the downward spiral of a 50-year-old movie star who resorts to drastic measures